Extremely disturbed after receiving a traumatic call for help from her 6-year-old niece, Lewis rushes from Chicago to New York to search for the child. Lewis tracks down her trouble-prone sister, Chloe, and enlists the aid of police officers Faith Yokas and Maurice "Bosco" Boscorelli and paramedics Kim Zambrano ("Third Watch" series star Kim Raver) and Alex Taylor. Sergeant Swersky also helps with the situation.